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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CFLAR
All Species:
8.18
Human Site:
T327
Identified Species:
20
UniProt:
O15519
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15519
NP_001120655.1
480
55344
T327
S
V
Y
G
V
D
Q
T
H
S
G
L
P
L
H
Chimpanzee
Pan troglodytes
XP_001171615
480
55346
T327
S
V
Y
G
V
D
Q
T
H
S
G
L
P
L
H
Rhesus Macaque
Macaca mulatta
XP_001096860
300
34118
I162
C
L
K
N
I
H
R
I
D
L
K
T
K
I
Q
Dog
Lupus familis
XP_545592
509
58483
T356
S
V
F
G
V
D
H
T
N
S
G
F
P
L
D
Cat
Felis silvestris
Mouse
Mus musculus
O35732
484
55227
V332
S
M
M
G
R
D
Q
V
H
S
G
F
S
L
D
Rat
Rattus norvegicus
NP_001029036
480
55041
V332
S
M
M
G
V
D
Q
V
Y
S
G
F
S
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507915
508
56290
A357
T
V
L
G
V
G
P
A
G
P
P
F
P
L
R
Chicken
Gallus gallus
Q98943
424
47941
N281
A
N
C
P
N
L
Q
N
K
P
K
M
F
F
I
Frog
Xenopus laevis
NP_001079034
500
57605
K325
K
T
L
E
M
Y
S
K
K
D
H
A
E
K
D
Zebra Danio
Brachydanio rerio
NP_919380
418
47600
L280
F
K
V
V
F
H
S
L
L
G
L
K
E
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
58.3
73.2
N.A.
66.7
68.7
N.A.
48.2
20.4
26.2
30.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
60.4
82.1
N.A.
78
79.5
N.A.
64.1
40
46.7
51
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
66.6
N.A.
53.3
53.3
N.A.
33.3
6.6
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
80
N.A.
60
66.6
N.A.
40
20
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% A
% Cys:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
50
0
0
10
10
0
0
0
0
30
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
20
0
10
% E
% Phe:
10
0
10
0
10
0
0
0
0
0
0
40
10
10
0
% F
% Gly:
0
0
0
60
0
10
0
0
10
10
50
0
0
0
0
% G
% His:
0
0
0
0
0
20
10
0
30
0
10
0
0
0
20
% H
% Ile:
0
0
0
0
10
0
0
10
0
0
0
0
0
10
10
% I
% Lys:
10
10
10
0
0
0
0
10
20
0
20
10
10
10
0
% K
% Leu:
0
10
20
0
0
10
0
10
10
10
10
20
0
60
0
% L
% Met:
0
20
20
0
10
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
10
0
10
10
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
10
0
0
20
10
0
40
0
0
% P
% Gln:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
20
% Q
% Arg:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
10
% R
% Ser:
50
0
0
0
0
0
20
0
0
50
0
0
20
0
0
% S
% Thr:
10
10
0
0
0
0
0
30
0
0
0
10
0
10
0
% T
% Val:
0
40
10
10
50
0
0
20
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
20
0
0
10
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _